Compile Data Set for Download or QSAR

Found 2 hits of ic50 for monomerid = 71349   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM71349 (US9546164, 420 | US9694002, 420) Show SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(C)(=O)=O)CN(C1)C(c1ccccc1)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C29H29Cl2FN2O4S/c1-29(15-34(16-29)27(19-6-4-3-5-7-19)20-10-21(30)12-22(31)11-20)17-38-26-14-25(32)24(13-23(26)18-8-9-18)28(35)33-39(2,36)37/h3-7,10-14,18,27H,8-9,15-17H2,1-2H3,(H,33,35)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...				US Patent US9546164 (2017) BindingDB Entry DOI: 10.7270/Q2JD4ZS4
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Sodium channel protein type 1/10/11/2/3/4/5/8/9 subunit alpha (Homo sapiens (Human))	BDBM71349 (US9546164, 420 | US9694002, 420) Show SMILES CC1(COc2cc(F)c(cc2C2CC2)C(=O)NS(C)(=O)=O)CN(C1)C(c1ccccc1)c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C29H29Cl2FN2O4S/c1-29(15-34(16-29)27(19-6-4-3-5-7-19)20-10-21(30)12-22(31)11-20)17-38-26-14-25(32)24(13-23(26)18-8-9-18)28(35)33-39(2,36)37/h3-7,10-14,18,27H,8-9,15-17H2,1-2H3,(H,33,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
GENENTECH, INC.; XENON PHARMACEUTICALS INC. US Patent					Assay Description Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...				US Patent US9694002 (2017) BindingDB Entry DOI: 10.7270/Q24B2ZFG
					More data for this Ligand-Target Pair