Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydrofolate reductase (Human pneumocystis pneumonia agent) | BDBM85933 (TMP | US11001595, Compound TMP) | MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University of The Holy Spirit US Patent | Assay Description TBD | US Patent US11001595 (2021) BindingDB Entry DOI: 10.7270/Q25M68TQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor (Rattus norvegicus (rat)-RAT-Rattus norvegicus (Rat...) | BDBM85933 (TMP | US11001595, Compound TMP) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
State University of New York Curated by ChEMBL | Assay Description Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine receptor in rat striatal membranes | Bioorg Med Chem Lett 14: 1799-802 (2004) Article DOI: 10.1016/j.bmcl.2003.12.097 BindingDB Entry DOI: 10.7270/Q2T43SJ8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Dihydrofolate reductase (Homo sapiens (Human)) | BDBM85933 (TMP | US11001595, Compound TMP) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 3.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Duquesne University of The Holy Spirit US Patent | Assay Description TBD | US Patent US11001595 (2021) BindingDB Entry DOI: 10.7270/Q25M68TQ | |||||||||||
More data for this Ligand-Target Pair |