Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Putative glycogen synthase kinase 3 alpha (Ustilago maydis (Smut fungus)) | BDBM92353 (Sorafenib derivative, 16) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität Dortmund | Assay Description Inhibition of UmGSK3 by kinase inhibitors. | ACS Chem Biol 7: 1257-67 (2012) Article DOI: 10.1021/cb300128b BindingDB Entry DOI: 10.7270/Q29S1PNH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM92353 (Sorafenib derivative, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01568 BindingDB Entry DOI: 10.7270/Q2MK6HMM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM92353 (Sorafenib derivative, 16) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universität Dortmund | Assay Description Inhibition of UmGSK3 by kinase inhibitors. | ACS Chem Biol 7: 1257-67 (2012) Article DOI: 10.1021/cb300128b BindingDB Entry DOI: 10.7270/Q29S1PNH | |||||||||||
More data for this Ligand-Target Pair |