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Compile Data Set for Download or QSAR

Found 2 hits of kd for monomerid = 7966   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H2 receptor


(Cavia porcellus (domestic guinea pig))
BDBM7966
PNG
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Show SMILES NCCc1cnc[nH]1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
PDB

UniProtKB/SwissProt

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CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
n/an/an/a 6.92E+4n/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Compound is evaluated for histamine H2 receptor agonistic activity in guinea pig cerebral cortex using [3H]tiotidine as radioligand


J Med Chem 35: 3239-46 (1992)


BindingDB Entry DOI: 10.7270/Q2C53N4J
More data for this
Ligand-Target Pair
Histamine H2 receptor


(RAT)
BDBM7966
PNG
(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Show SMILES NCCc1cnc[nH]1
Show InChI InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
PDB

KEGG

UniProtKB/SwissProt

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AffyNet 
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CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
n/an/an/a 1.17E+5n/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Affinity to the Histamine H2 receptor was determined expressed in CHO cell using [125I]iodoaminopotentidine as radioligand


Bioorg Med Chem Lett 4: 1913-1916 (1994)


Article DOI: 10.1016/S0960-894X(01)80533-3
BindingDB Entry DOI: 10.7270/Q2TD9ZHX
More data for this
Ligand-Target Pair