Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Baculoviral IAP repeat-containing protein 2 [253-363] (Homo sapiens (Human)) | BDBM26207 ((2R,5S,8S)-8-[(2S)-2-(methylamino)propanamido]-7-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.10 | -50.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Shanghai Institute of Organic Chemistry | Assay Description Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri... | J Med Chem 51: 7352-5 (2008) Article DOI: 10.1021/jm801146d BindingDB Entry DOI: 10.7270/Q2HQ3X7Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Baculoviral IAP repeat-containing protein 3 [238-349] (Homo sapiens (Human)) | BDBM26207 ((2R,5S,8S)-8-[(2S)-2-(methylamino)propanamido]-7-o...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 4.20 | -47.3 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Shanghai Institute of Organic Chemistry | Assay Description Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri... | J Med Chem 51: 7352-5 (2008) Article DOI: 10.1021/jm801146d BindingDB Entry DOI: 10.7270/Q2HQ3X7Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
E3 ubiquitin-protein ligase XIAP [241-356] (Homo sapiens (Human)) | BDBM26207 ((2R,5S,8S)-8-[(2S)-2-(methylamino)propanamido]-7-o...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 18 | -43.8 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
Shanghai Institute of Organic Chemistry | Assay Description Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri... | J Med Chem 51: 7352-5 (2008) Article DOI: 10.1021/jm801146d BindingDB Entry DOI: 10.7270/Q2HQ3X7Z | |||||||||||
More data for this Ligand-Target Pair |