Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 291119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Homo sapiens (Human))	BDBM291119 (US9580396, Example 2k) Show SMILES CN1C(=N)N[C@@]2(CCOc3ccc(NC(=O)c4ncc(cc4C)C#N)cc23)CS1(=O)=O |r| Show InChI InChI=1S/C20H20N6O4S/c1-12-7-13(9-21)10-23-17(12)18(27)24-14-3-4-16-15(8-14)20(5-6-30-16)11-31(28,29)26(2)19(22)25-20/h3-4,7-8,10H,5-6,11H2,1-2H3,(H2,22,25)(H,24,27)/t20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	5.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...				US Patent US9580396 (2017) BindingDB Entry DOI: 10.7270/Q29K4D9S
					More data for this Ligand-Target Pair
Beta-secretase 2 (Homo sapiens (Human))	BDBM291119 (US9580396, Example 2k) Show SMILES CN1C(=N)N[C@@]2(CCOc3ccc(NC(=O)c4ncc(cc4C)C#N)cc23)CS1(=O)=O |r| Show InChI InChI=1S/C20H20N6O4S/c1-12-7-13(9-21)10-23-17(12)18(27)24-14-3-4-16-15(8-14)20(5-6-30-16)11-31(28,29)26(2)19(22)25-20/h3-4,7-8,10H,5-6,11H2,1-2H3,(H2,22,25)(H,24,27)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	26	n/a	n/a	n/a	n/a	n/a	n/a	5.0	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description Inhibitor IC50s at purified human autoBACE-2 are determined in a time-resolved endpoint proteolysis assay that measures hydrolysis of the QSY7-EISEVN...				US Patent US9580396 (2017) BindingDB Entry DOI: 10.7270/Q29K4D9S
					More data for this Ligand-Target Pair