Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Urokinase-type plasminogen activator (Homo sapiens (Human)) | BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against the enzyme Urokinase-type plasminogen activator | J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prothrombin (Homo sapiens (Human)) | BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 3.79E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against the enzyme thrombin | J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen (Homo sapiens (Human)) | BDBM50003742 ((Lactone1)N-[4-(6-Methylene-2-oxo-tetrahydro-pyran...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 4.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Compound was tested for its binding affinity against the enzyme plasmin | J Med Chem 35: 4297-305 (1992) BindingDB Entry DOI: 10.7270/Q2TD9W9D | |||||||||||
More data for this Ligand-Target Pair |