BindingDB PrimarySearch

Found 22 hits of ki for monomerid = 50006584
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Curated by PDSP K_i Database									J Pharmacol Exp Ther 256: 689-94 (1991) BindingDB Entry DOI: 10.7270/Q25T3J06
University of Arizona Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description In vitro binding affinity for muscarinic M1 receptor by displacing [3H]-Pirenzepine binding on rat brain homogenate.				J Med Chem 37: 4085-99 (1995) BindingDB Entry DOI: 10.7270/Q21N8066
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by liquid scintillation counter				J Med Chem 51: 3905-12 (2008) Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO cells by microplate scintillation counting				Bioorg Med Chem 17: 8174-85 (2009) Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M1 receptor transfected in CHO cells after 120 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 3255-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by liquid scintillation counter				J Med Chem 51: 3905-12 (2008) Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO cells by microplate scintillation counting				Bioorg Med Chem 17: 8174-85 (2009) Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M3 receptor transfected in CHO cells after 120 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 3255-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	2.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Binding affinity to Muscarinic acetylcholine receptor M3 by measuring its ability to displace [3H]N-methylscopolamine binding in rat submandibulary g...				J Med Chem 41: 3220-31 (1998) Article DOI: 10.1021/jm9708588 BindingDB Entry DOI: 10.7270/Q2M32ZH9
National University of Singapore Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO cells by liquid scintillation counter				J Med Chem 51: 3905-12 (2008) Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO cells by microplate scintillation counting				Bioorg Med Chem 17: 8174-85 (2009) Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M2 receptor transfected in CHO cells after 120 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 3255-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO cells by liquid scintillation counter				J Med Chem 51: 3905-12 (2008) Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor expressed in CHO cells by microplate scintillation counting				Bioorg Med Chem 17: 8174-85 (2009) Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M5 receptor transfected in CHO cells after 120 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 3255-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Binding affinity to Muscarinic acetylcholine receptor M1 by measuring its ability to displace [3H]pirenzepine from rat cerebral cortex				J Med Chem 41: 3220-31 (1998) Article DOI: 10.1021/jm9708588 BindingDB Entry DOI: 10.7270/Q2M32ZH9
National University of Singapore Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Binding affinity to Muscarinic acetylcholine receptor M2 by measuring its ability to displace [3H]N-methylscopolamine binding in rat heart				J Med Chem 41: 3220-31 (1998) Article DOI: 10.1021/jm9708588 BindingDB Entry DOI: 10.7270/Q2M32ZH9
National University of Singapore Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Health Science Center Curated by PDSP K_i Database									Life Sci 50: 355-63 (1992) Article DOI: 10.1016/0024-3205(92)90437-t BindingDB Entry DOI: 10.7270/Q2XK8D19
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor transfected in CHO cells after 120 mins by scintillation counting analysis				Bioorg Med Chem Lett 24: 3255-9 (2014) Article DOI: 10.1016/j.bmcl.2014.06.020 BindingDB Entry DOI: 10.7270/Q2WW7KBT
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Firenze Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO cells by liquid scintillation counter				J Med Chem 51: 3905-12 (2008) Article DOI: 10.1021/jm800145d BindingDB Entry DOI: 10.7270/Q2TX3GMC
Universit£ di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	9.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human muscarinic M4 receptor expressed in CHO cells by microplate scintillation counting				Bioorg Med Chem 17: 8174-85 (2009) Article DOI: 10.1016/j.bmc.2009.10.027 BindingDB Entry DOI: 10.7270/Q2125TW3
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (RAT)	BDBM50006584 ((McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2...) Show SMILES C[N+](C)(C)CC#CCOC(=O)Nc1cccc(Cl)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Arizona Health Science Center Curated by PDSP K_i Database									Life Sci 50: 355-63 (1992) Article DOI: 10.1016/0024-3205(92)90437-t BindingDB Entry DOI: 10.7270/Q2XK8D19
					More data for this Ligand-Target Pair