Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
3-oxo-5-alpha-steroid 4-dehydrogenase 2 (Homo sapiens (Human)) | BDBM50009101 (4-Benzyloxy-1H-indole-2-carboxylic acid | CHEMBL23...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition constant against recombinant human Steroid 5-alpha-reductase type 2 expressed in CHO cells | J Med Chem 38: 13-5 (1995) BindingDB Entry DOI: 10.7270/Q2D50P5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (Homo sapiens (Human)) | BDBM50009101 (4-Benzyloxy-1H-indole-2-carboxylic acid | CHEMBL23...) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SmithKline Beecham Pharmaceuticals Curated by ChEMBL | Assay Description Apparent inhibition constant against recombinant human Steroid 5-alpha-reductase type I expressed in CHO cells | J Med Chem 38: 13-5 (1995) BindingDB Entry DOI: 10.7270/Q2D50P5K | |||||||||||
More data for this Ligand-Target Pair |