Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C (Homo sapiens (Human)) | BDBM50020874 ((3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of human brain | J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human)) | BDBM50020874 ((3-Chloro-phenyl)-(4-phenyl-phthalazin-1-yl)-amine...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Binding affinity for low Km cAMP phosphodiesterase PDE III of human platelets | J Med Chem 28: 537-45 (1985) BindingDB Entry DOI: 10.7270/Q2N58MXT | |||||||||||
More data for this Ligand-Target Pair |