BindingDB PrimarySearch

Found 10 hits of ki for monomerid = 50026752
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	412	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]-paroxetine from serotonin transporter (SERT)				Bioorg Med Chem Lett 9: 3273-6 (2000) BindingDB Entry DOI: 10.7270/Q23F4NVM
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]paroxetine binding to rat serotonin transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from serotonin transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	451	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity of the compound against mu opioid receptor was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]DAMGO binding to mu-opioid receptor				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	DrugBank Article PubMed	920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Binding affinity at mu-opioid receptor				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]WIN 35428 from dopamine transporter in Sprague-Dawley rat brain after 1 hr by liquid scintillation counting				Bioorg Med Chem 18: 8356-64 (2010) Article DOI: 10.1016/j.bmc.2010.09.060 BindingDB Entry DOI: 10.7270/Q2CN744P
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 binding to rat dopamine transporter				J Med Chem 48: 1336-43 (2005) Article DOI: 10.1021/jm0401614 BindingDB Entry DOI: 10.7270/Q2PZ59KQ
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]-WIN- 35,428 from dopamine transporter (DAT)				Bioorg Med Chem Lett 9: 3273-6 (2000) BindingDB Entry DOI: 10.7270/Q23F4NVM
University of New Orleans Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Cavia porcellus (domestic guinea pig))	BDBM50026752 (1-Methyl-4-phenyl-piperidine-4-carboxylic acid eth...) Show SMILES CCOC(=O)C1(CCN(C)CC1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Taiwan University Curated by ChEMBL					Assay Description Binding affinity of the compound against Opioid receptor kappa 1 was determined in brain membrane preparations from male Hartley guinea-pigs				Bioorg Med Chem Lett 8: 1813-8 (1999) BindingDB Entry DOI: 10.7270/Q2K073D5
National Taiwan University Curated by ChEMBL					More data for this Ligand-Target Pair