BindingDB PrimarySearch

Found 15 hits of ki for monomerid = 50063917
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human tumor necrosis factor-alpha converting enzyme				Bioorg Med Chem Lett 13: 2741-4 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10DK
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human TNF-alpha converting enzyme (TACE)				Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical Research Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory potency against Matrix metalloprotease-2 (MMP-2)				J Med Chem 45: 2289-93 (2002) Article DOI: 10.1021/jm0110993 BindingDB Entry DOI: 10.7270/Q2HQ42NC
Preclinical Research Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical Research Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory potency against Matrix metalloprotease-1 (MMP-1)				J Med Chem 45: 2289-93 (2002) Article DOI: 10.1021/jm0110993 BindingDB Entry DOI: 10.7270/Q2HQ42NC
Preclinical Research Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description In vitro inhibition of human MMP-1.				J Med Chem 44: 2636-60 (2001) BindingDB Entry DOI: 10.7270/Q2FB53NR
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description In vitro inhibition of human MMP-9.				J Med Chem 44: 2636-60 (2001) BindingDB Entry DOI: 10.7270/Q2FB53NR
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human matrix metalloproteinase-1				Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of Recombinant human matrix metalloproteinase-1				Bioorg Med Chem Lett 13: 2741-4 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10DK
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
DuPont Pharmaceuticals Company Curated by ChEMBL					Assay Description Inhibition of human MMP-3.				J Med Chem 44: 2636-60 (2001) BindingDB Entry DOI: 10.7270/Q2FB53NR
DuPont Pharmaceuticals Company Curated by ChEMBL					More data for this Ligand-Target Pair
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical Research Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory potency against Tumor necrosis factor alpha converting enzyme (TACE)				J Med Chem 45: 2289-93 (2002) Article DOI: 10.1021/jm0110993 BindingDB Entry DOI: 10.7270/Q2HQ42NC
Preclinical Research Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Preclinical Research Novartis Pharma AG Curated by ChEMBL					Assay Description Inhibitory potency against Matrix metalloprotease-3 (MMP-3)				J Med Chem 45: 2289-93 (2002) Article DOI: 10.1021/jm0110993 BindingDB Entry DOI: 10.7270/Q2HQ42NC
Preclinical Research Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human matrix metalloproteinase-9 (gelatinase B)				Bioorg Med Chem Lett 13: 2741-4 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10DK
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human matrix metalloproteinase-9				Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human matrix metalloproteinase-3				Bioorg Med Chem Lett 13: 2741-4 (2003) BindingDB Entry DOI: 10.7270/Q2JQ10DK
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair
Stromelysin-1 (Homo sapiens (Human))	BDBM50063917 ((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido Collaboration Center Curated by ChEMBL					Assay Description Inhibition of recombinant human matrix metalloproteinase-3				Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG
Hokkaido Collaboration Center Curated by ChEMBL					More data for this Ligand-Target Pair