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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50078236   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Rattus norvegicus)
BDBM50078236
PNG
(2-(2,6-Dichloro-phenyl)-5-(2-methoxy-phenyl)-7-met...)
Show SMILES COc1ccccc1C1N2C=C(SC2=NC(C)=C1C(=O)OCCCN(C)C)c1c(Cl)cccc1Cl |c:11,15,18|
Show InChI InChI=1S/C26H27Cl2N3O3S/c1-16-22(25(32)34-14-8-13-30(2)3)24(17-9-5-6-12-20(17)33-4)31-15-21(35-26(31)29-16)23-18(27)10-7-11-19(23)28/h5-7,9-12,15,24H,8,13-14H2,1-4H3
PDB

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.40E+3n/an/an/an/an/an/an/an/a



F. Hoffmann-La Roche Ltd.

Curated by ChEMBL


Assay Description
Inhibition of 1S,3R-ACPD (10 microM) -stimulated GTP gamma 35S binding on rat Metabotropic glutamate receptor 2 transfected in CHO cells


Bioorg Med Chem Lett 9: 1573-6 (1999)


BindingDB Entry DOI: 10.7270/Q2XS5TKC
More data for this
Ligand-Target Pair