Found 4 hits of ki for monomerid = 50087869 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50087869
(CHEMBL3426914)Show SMILES [Na+].[Na+].[Na+].[Na+].CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(=O)P(O)([O-])=O)NC(=O)[C@H](CCC([O-])=O)NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](C)NC(=O)[C@H](CC([O-])=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C34H48N7O17P.4Na/c1-15(2)11-21(28(35)49)39-32(53)22(12-18-5-7-19(8-6-18)34(55)59(56,57)58)41-30(51)20(9-10-25(43)44)38-33(54)24(14-27(47)48)40-29(50)16(3)36-31(52)23(13-26(45)46)37-17(4)42;;;;/h5-8,15-16,20-24H,9-14H2,1-4H3,(H2,35,49)(H,36,52)(H,37,42)(H,38,54)(H,39,53)(H,40,50)(H,41,51)(H,43,44)(H,45,46)(H,47,48)(H2,56,57,58);;;;/q;4*+1/p-4/t16-,20-,21-,22-,23-,24-;;;;/m0..../s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 390 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin
Curated by ChEMBL
| Assay Description
Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow... |
Bioorg Med Chem 23: 2839-47 (2015)
Article DOI: 10.1016/j.bmc.2015.03.074
BindingDB Entry DOI: 10.7270/Q2QN68H0 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50087869
(CHEMBL3426914)Show SMILES [Na+].[Na+].[Na+].[Na+].CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(=O)P(O)([O-])=O)NC(=O)[C@H](CCC([O-])=O)NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](C)NC(=O)[C@H](CC([O-])=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C34H48N7O17P.4Na/c1-15(2)11-21(28(35)49)39-32(53)22(12-18-5-7-19(8-6-18)34(55)59(56,57)58)41-30(51)20(9-10-25(43)44)38-33(54)24(14-27(47)48)40-29(50)16(3)36-31(52)23(13-26(45)46)37-17(4)42;;;;/h5-8,15-16,20-24H,9-14H2,1-4H3,(H2,35,49)(H,36,52)(H,37,42)(H,38,54)(H,39,53)(H,40,50)(H,41,51)(H,43,44)(H,45,46)(H,47,48)(H2,56,57,58);;;;/q;4*+1/p-4/t16-,20-,21-,22-,23-,24-;;;;/m0..../s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin
Curated by ChEMBL
| Assay Description
Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins follow... |
Bioorg Med Chem 23: 2839-47 (2015)
Article DOI: 10.1016/j.bmc.2015.03.074
BindingDB Entry DOI: 10.7270/Q2QN68H0 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50087869
(CHEMBL3426914)Show SMILES [Na+].[Na+].[Na+].[Na+].CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(=O)P(O)([O-])=O)NC(=O)[C@H](CCC([O-])=O)NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](C)NC(=O)[C@H](CC([O-])=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C34H48N7O17P.4Na/c1-15(2)11-21(28(35)49)39-32(53)22(12-18-5-7-19(8-6-18)34(55)59(56,57)58)41-30(51)20(9-10-25(43)44)38-33(54)24(14-27(47)48)40-29(50)16(3)36-31(52)23(13-26(45)46)37-17(4)42;;;;/h5-8,15-16,20-24H,9-14H2,1-4H3,(H2,35,49)(H,36,52)(H,37,42)(H,38,54)(H,39,53)(H,40,50)(H,41,51)(H,43,44)(H,45,46)(H,47,48)(H2,56,57,58);;;;/q;4*+1/p-4/t16-,20-,21-,22-,23-,24-;;;;/m0..../s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.73E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin
Curated by ChEMBL
| Assay Description
Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs... |
Bioorg Med Chem 23: 2839-47 (2015)
Article DOI: 10.1016/j.bmc.2015.03.074
BindingDB Entry DOI: 10.7270/Q2QN68H0 |
More data for this
Ligand-Target Pair | |
Tyrosine-protein phosphatase non-receptor type 1
(Homo sapiens (Human)) | BDBM50087869
(CHEMBL3426914)Show SMILES [Na+].[Na+].[Na+].[Na+].CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(cc1)C(=O)P(O)([O-])=O)NC(=O)[C@H](CCC([O-])=O)NC(=O)[C@H](CC([O-])=O)NC(=O)[C@H](C)NC(=O)[C@H](CC([O-])=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C34H48N7O17P.4Na/c1-15(2)11-21(28(35)49)39-32(53)22(12-18-5-7-19(8-6-18)34(55)59(56,57)58)41-30(51)20(9-10-25(43)44)38-33(54)24(14-27(47)48)40-29(50)16(3)36-31(52)23(13-26(45)46)37-17(4)42;;;;/h5-8,15-16,20-24H,9-14H2,1-4H3,(H2,35,49)(H,36,52)(H,37,42)(H,38,54)(H,39,53)(H,40,50)(H,41,51)(H,43,44)(H,45,46)(H,47,48)(H2,56,57,58);;;;/q;4*+1/p-4/t16-,20-,21-,22-,23-,24-;;;;/m0..../s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Freie Universit£t Berlin
Curated by ChEMBL
| Assay Description
Inhibition of PTP1B catalytic domain (1 to 321 amino acids) (unknown origin) expressed in Escherichia coli Rosetta (DE3) incubated for 30 mins in abs... |
Bioorg Med Chem 23: 2839-47 (2015)
Article DOI: 10.1016/j.bmc.2015.03.074
BindingDB Entry DOI: 10.7270/Q2QN68H0 |
More data for this
Ligand-Target Pair | |
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