Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Transcription factor 7-like 2 (Homo sapiens (Human)) | BDBM50094600 (CHEMBL2323029) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay | ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Catenin beta-1 (Homo sapiens (Human)) | BDBM50094600 (CHEMBL2323029) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after... | J Med Chem 58: 4678-92 (2015) Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transcription factor 7-like 2 (Homo sapiens (Human)) | BDBM50094600 (CHEMBL2323029) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay | ACS Med Chem Lett 4: 306-11 (2013) Article DOI: 10.1021/ml300367f BindingDB Entry DOI: 10.7270/Q2CN76TG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Catenin beta-1 (Homo sapiens (Human)) | BDBM50094600 (CHEMBL2323029) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah Curated by ChEMBL | Assay Description Inhibition of N-terminally His6-tagged human beta-catenin (residues 138-686)/C-terminally biotinylated human Tcf4 (residues 7-51) interaction after 4... | J Med Chem 58: 4678-92 (2015) Article DOI: 10.1021/acs.jmedchem.5b00223 BindingDB Entry DOI: 10.7270/Q2G44S28 | |||||||||||
More data for this Ligand-Target Pair |