Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50118293 (7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 27.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Inhibition of [125I]- RTI -55 binding at the Dopamine transporter sites on HEK-hDAT cells | J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50118293 (7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 33.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Inhibition of [125I]- RTI -55 binding at the Norepinephrin transpoter sites on HEK-hNET cells | J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50118293 (7-(4-Chloro-phenyl)-8,9-dihydro-7H-7a,10-diaza-pen...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 224 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Drew University Curated by ChEMBL | Assay Description Inhibition of [125I]- RTI -55 binding at the Serotonin transporter sites on HEK-hSERT cells | J Med Chem 45: 4110-8 (2002) BindingDB Entry DOI: 10.7270/Q25Q4VF3 | |||||||||||
More data for this Ligand-Target Pair |