Compile Data Set for Download or QSAR

Found 10 hits of ki for monomerid = 50122799   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A adrenergic receptor (CALF)	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin (0.3 nM) from bovine Alpha-1A adrenergic receptor expressed in BHK cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
Alpha-1B adrenergic receptor (C.H.O.)	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin (0.5 nM) from hamster Alpha-1B adrenergic receptor expressed in rat-1 cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin (0.3 nM) from rat Alpha-1D adrenergic receptor expressed in CHO cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Ability to displace [3H]5-CT (2.0 nM) from HeLa cells of human 5-hydroxytryptamine 1A receptor				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Ability to displace [3H]5-CT (1.5 nM) from HeLa cells of human 5-hydroxytryptamine 1B receptor				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin (0.5 nM) from rat cerebral cortex 5-hydroxytryptamine 2A receptors				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine (0.5 nM) from rat 5-hydroxytryptamine 2C receptor expressed in SR-3T3 cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]spiperone (0.5 nM) from rat corpus striatum dopamine D2 receptor				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Ability to displace [3H]spiperone (0.3 nM) from CHO cells of human Dopamine receptor D3				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50122799 (1-(2-{4-[1-(4-Fluoro-phenyl)-5-(1-methyl-1H-pyrazo...) Show SMILES Cn1ccc(n1)-c1ccc2n(cc(C3CCN(CCN4CCNC4=O)CC3)c2c1)-c1ccc(F)cc1 Show InChI InChI=1S/C28H31FN6O/c1-32-12-10-26(31-32)21-2-7-27-24(18-21)25(19-35(27)23-5-3-22(29)4-6-23)20-8-13-33(14-9-20)16-17-34-15-11-30-28(34)36/h2-7,10,12,18-20H,8-9,11,13-17H2,1H3,(H,30,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]-YM-09151-2 (0.06 nM) from human Dopamine receptor D4 expressed in CHO cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
					More data for this Ligand-Target Pair