Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl | CHEMBL875...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Kinetic inhibition constant of compound with Trypanosoma cruzi Hypoxanthine Phosphoribosyltransferase (HPRT) | J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl | CHEMBL875...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Kinetic inhibition constant of compound with human Hypoxanthine Phosphoribosyltransferase (HPRT) | J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hypoxanthine-guanine phosphoribosyltransferase (Homo sapiens (Human)) | BDBM50128867 (3,5-diphenyl-4'-methyl-2-nitrobiphenyl | CHEMBL875...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | 1.39E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut Curated by ChEMBL | Assay Description Kinetic inhibition constant of compound with bacterial Hypoxanthine Phosphoribosyltransferase (HPRT) | J Med Chem 46: 2548-50 (2003) Article DOI: 10.1021/jm030061i BindingDB Entry DOI: 10.7270/Q2CF9PGG | |||||||||||
More data for this Ligand-Target Pair |