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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50132896   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))
BDBM50132896
PNG
(CHEMBL114193 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
3.30n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells


Bioorg Med Chem Lett 13: 3371-4 (2003)


BindingDB Entry DOI: 10.7270/Q21C1W8F
More data for this
Ligand-Target Pair
Corticotropin-releasing factor receptor 1


(Homo sapiens (Human))
BDBM50132896
PNG
(CHEMBL114193 | [3-(2,4-Dichloro-phenyl)-1,5-dimeth...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C20H24Cl2N4/c1-5-9-26(10-6-2)17-11-13(3)23-19-18(24-25(4)20(17)19)15-8-7-14(21)12-16(15)22/h7-8,11-12H,5-6,9-10H2,1-4H3
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
3.30n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells


Bioorg Med Chem Lett 13: 3367-70 (2003)


BindingDB Entry DOI: 10.7270/Q2542N05
More data for this
Ligand-Target Pair