Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50133171 (CHEMBL3634821) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]ketanserine from 5-HT2A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50133171 (CHEMBL3634821) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatum homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50133171 (CHEMBL3634821) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from 5-HT7 receptor in rat hypothalamus homogenates after 120 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat)) | BDBM50133171 (CHEMBL3634821) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50133171 (CHEMBL3634821) | PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.99E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]mesulergine from 5-HT2C receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Histamine H1 receptor (Cavia porcellus (domestic guinea pig)) | BDBM50133171 (CHEMBL3634821) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Huazhong University of Science and Technology Curated by ChEMBL | Assay Description Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum homogenates after 60 mins by liquid scintillation counting | Bioorg Med Chem Lett 25: 5299-305 (2015) Article DOI: 10.1016/j.bmcl.2015.09.045 BindingDB Entry DOI: 10.7270/Q26W9CW2 | |||||||||||
More data for this Ligand-Target Pair |