Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50184869 (1-(4-(6,7-dimethoxyquinolin-4-yloxy)phenyl)-3-(2-p...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Inhibition of human activated c-Met by PK/LDH coupled kinetic assay | Eur J Med Chem 43: 1321-9 (2008) Article DOI: 10.1016/j.ejmech.2007.08.011 BindingDB Entry DOI: 10.7270/Q2HX1CGS | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |