Found 30 hits of ki for monomerid = 50187377 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT1A receptor in rat cerebral cortex by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Rattus norvegicus (rat)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pierre Fabre Research Center
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT1A receptor in rat cortex membrane |
J Med Chem 50: 5024-33 (2007)
Article DOI: 10.1021/jm070714l
BindingDB Entry DOI: 10.7270/Q2HH6NTB |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to guinea pig sigma receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 7
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT7 receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor
(Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to potassium channel by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Cholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to cholecystokinin receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 1/2/3/4/5
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to somatostatin receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Nociceptin receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to orphanin receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to D2 receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | NCI pathway
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to dopamine transporter by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Rattus norvegicus (Rat)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT1B receptor in rat cerebral cortex by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Beta-1/Beta-2/Beta-3 adrenergic receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
MMDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to beta adrenergic receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Type-1/Type-2 angiotensin II receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to angiotensin2 receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
D(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to dopamine receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1/M2/M3/M4/M5
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
MMDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to muscarinic receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Delta-type/Kappa-type/Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to opioid receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Translocator protein
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | KEGG
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to benzodiazepine receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Endothelin receptor type B/1 receptor
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to endothelin receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
MMDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2A receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Sigma non-opioid intracellular receptor 1
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to sigma receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | Reactome pathway
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to norepinephrine transporter by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to bovine 5HT1D receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 5A
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT5A receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT2C receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 6
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT6 receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to 5HT2B receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 3A/3B
(Mus musculus (house mouse)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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| >5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to mouse 5HT3 receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
5-hydroxytryptamine receptor 4
(Homo sapiens (Human)) | BDBM50187377
(CHEMBL209821 | N-(3-(4-(4-(cyclohexylmethylsulfona...)Show SMILES CC(=O)Nc1cccc(c1)N1CCN(CCCCNS(=O)(=O)CC2CCCCC2)CC1 Show InChI InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28) | PDB
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Predix Pharmaceuticals Ltd.
Curated by ChEMBL
| Assay Description
Binding affinity to human 5HT4e receptor by radioligand binding assay |
J Med Chem 49: 3116-35 (2006)
Article DOI: 10.1021/jm0508641
BindingDB Entry DOI: 10.7270/Q2319VHC |
More data for this
Ligand-Target Pair | |
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