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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50211257   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol lipase-alpha


(Mus musculus)		BDBM50211257
PNG
(CHEMBL3895863 | US10583137, Compound 14)
Show SMILES OC(c1cnn(n1)C(=O)N1C[C@@H](CC[C@@H]1Cc1ccccc1)OCC#C)(c1ccc(F)cc1)c1ccc(F)cc1 |r|
Show InChI InChI=1S/C31H28F2N4O3/c1-2-18-40-28-17-16-27(19-22-6-4-3-5-7-22)36(21-28)30(38)37-34-20-29(35-37)31(39,23-8-12-25(32)13-9-23)24-10-14-26(33)15-11-24/h1,3-15,20,27-28,39H,16-19,21H2/t27-,28-/m1/s1
UniProtKB/SwissProt

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CHEMBL
MCE
PC cid
PC sid
UniChem

Similars
Article
PubMed
 0.270n/an/an/an/an/an/an/an/a



Leiden University

Curated by ChEMBL


Assay Description
Inhibition of mouse DAGL-alpha expressed in HEK293T cell membranes assessed as inhibition constant pre-incubated for 20 mins before PNP-butyrate subs...

J Med Chem 62: 7910-7922 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00686
BindingDB Entry DOI: 10.7270/Q2GQ724G
More data for this
Ligand-Target Pair