Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Solute carrier organic anion transporter family member (Danio rerio (Zebrafish)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 360 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Rudjer Boskovic Institute | Assay Description In the inhibition experiments, the cells were preincubated for 20 s with test compounds, followed by a 5-min incubation with [3H]E3S (5 nM) or 30-min... | J Biol Chem 288: 33894-911 (2013) Article DOI: 10.1074/jbc.M113.518506 BindingDB Entry DOI: 10.7270/Q29Z93RK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Rattus norvegicus (Rat)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 600 | -36.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Institut National de Recherche Agronomique (INRA)-Vetagro Sup, Veterinary School of Lyon | Assay Description Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1... | J Biol Chem 288: 28733-42 (2013) Article DOI: 10.1074/jbc.M113.457119 BindingDB Entry DOI: 10.7270/Q27943HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1 (Homo sapiens (Human)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 1.80E+3 | -34.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Institut National de Recherche Agronomique (INRA)-Vetagro Sup, Veterinary School of Lyon | Assay Description Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1... | J Biol Chem 288: 28733-42 (2013) Article DOI: 10.1074/jbc.M113.457119 BindingDB Entry DOI: 10.7270/Q27943HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | DrugBank Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca R&D Curated by ChEMBL | Assay Description Binding affinity towards cytochrome P450 2C9 | J Med Chem 47: 907-14 (2004) Article DOI: 10.1021/jm030972s BindingDB Entry DOI: 10.7270/Q2ZK5HF3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1-like protein 1 (Rattus norvegicus (Rat)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 3.26E+4 | -26.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Institut National de Recherche Agronomique (INRA)-Vetagro Sup, Veterinary School of Lyon | Assay Description Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1... | J Biol Chem 288: 28733-42 (2013) Article DOI: 10.1074/jbc.M113.457119 BindingDB Entry DOI: 10.7270/Q27943HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vitamin K epoxide reductase complex subunit 1-like protein 1 (Homo sapiens (Human)) | BDBM50343352 (2-hydroxy-3-(3-oxo-1-phenylbutyl)-4H-chromen-4-one...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | 5.20E+4 | -25.4 | n/a | n/a | n/a | n/a | n/a | 7.4 | 37 |
Institut National de Recherche Agronomique (INRA)-Vetagro Sup, Veterinary School of Lyon | Assay Description Briefly, standard reactions were performed in 200 mM Hepes buffer, pH 7.4, containing 150 mM KCl, 1 mM dithiothreitol, 0.25 to 2 g liter-1... | J Biol Chem 288: 28733-42 (2013) Article DOI: 10.1074/jbc.M113.457119 BindingDB Entry DOI: 10.7270/Q27943HC | |||||||||||
More data for this Ligand-Target Pair |