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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50356472   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neuronal acetylcholine receptor subunit alpha-7


(Rattus norvegicus (Rat))		BDBM50356472
PNG
(CHEMBL1911862)
Show SMILES Nc1c(oc2ccccc12)C1=NC2(CN1)CN1CCC2CC1 |t:12,(17.47,-38.07,;17.87,-36.58,;16.89,-35.39,;17.73,-34.09,;19.22,-34.49,;20.51,-33.66,;21.87,-34.35,;21.96,-35.9,;20.66,-36.73,;19.3,-36.03,;15.35,-35.48,;14.51,-36.77,;13.03,-36.37,;12.95,-34.83,;14.38,-34.28,;13.03,-37.92,;11.7,-38.68,;10.37,-37.92,;10.37,-36.38,;11.7,-35.6,;12.45,-36.93,;11.11,-37.69,)|
Show InChI InChI=1S/C17H20N4O/c18-14-12-3-1-2-4-13(12)22-15(14)16-19-9-17(20-16)10-21-7-5-11(17)6-8-21/h1-4,11H,5-10,18H2,(H,19,20)
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PC cid
PC sid
UniChem
Article
PubMed
 120n/an/an/an/an/an/an/an/a



Targacept Inc

Curated by ChEMBL


Assay Description
Displacement of [3H]-methyllycaconitine from alpha7 nAChR in rat hippocampal membranes after 2 hrs by liquid scintillation counting

Eur J Med Chem 46: 5625-35 (2011)


Article DOI: 10.1016/j.ejmech.2011.09.033
BindingDB Entry DOI: 10.7270/Q2639Q4D
More data for this
Ligand-Target Pair