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Compile Data Set for Download or QSAR

Found 2 hits of ki for monomerid = 50372961   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50372961
PNG
(CHEMBL403921)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(CC2(Cc2ccc(F)cc2)C1)cnn3-c1ccc(F)cc1 |w:18.20,t:14|
Show InChI InChI=1S/C30H27F2N3O2S/c1-21-2-12-28(13-3-21)38(36,37)34-15-14-24-16-29-23(19-33-35(29)27-10-8-26(32)9-11-27)18-30(24,20-34)17-22-4-6-25(31)7-5-22/h2-13,16,19H,14-15,17-18,20H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.5n/an/an/an/an/an/an/an/a



Corcept Therapeutics

Curated by ChEMBL


Assay Description
Displacement of [3H]dexamethasone from human recombinant GR


Bioorg Med Chem Lett 18: 1312-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.027
BindingDB Entry DOI: 10.7270/Q22Z16CP
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50372961
PNG
(CHEMBL403921)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1CCC2=Cc3c(CC2(Cc2ccc(F)cc2)C1)cnn3-c1ccc(F)cc1 |w:18.20,t:14|
Show InChI InChI=1S/C30H27F2N3O2S/c1-21-2-12-28(13-3-21)38(36,37)34-15-14-24-16-29-23(19-33-35(29)27-10-8-26(32)9-11-27)18-30(24,20-34)17-22-4-6-25(31)7-5-22/h2-13,16,19H,14-15,17-18,20H2,1H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
17n/an/an/an/an/an/an/an/a



Corcept Therapeutics

Curated by ChEMBL


Assay Description
Antagonist activity at GR in SW1353/MMTV5 cells assessed as inhibition of dexamethasone-induced luciferase expression


Bioorg Med Chem Lett 18: 1312-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.01.027
BindingDB Entry DOI: 10.7270/Q22Z16CP
More data for this
Ligand-Target Pair