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Compile Data Set for Download or QSAR

Found 1 hit of ki for monomerid = 50405082   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dihydrofolate reductase


(Gallus gallus (Chicken))
BDBM50405082
PNG
(CHEMBL286618)
Show SMILES Cc1cccc(OCCOc2cccc(c2)N2C(N)=NC(N)=NC2(C)C)c1 |c:19,22|
Show InChI InChI=1S/C20H25N5O2/c1-14-6-4-8-16(12-14)26-10-11-27-17-9-5-7-15(13-17)25-19(22)23-18(21)24-20(25,2)3/h4-9,12-13H,10-11H2,1-3H3,(H4,21,22,23,24)
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PC sid
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Similars

PubMed
95n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against isolated chicken liver dihydrofolate reductase (DHFR)


J Med Chem 27: 129-43 (1984)


BindingDB Entry DOI: 10.7270/Q2TT4S5M
More data for this
Ligand-Target Pair