Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50174292'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50174292 (3-(4-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)bicy...) Show SMILES Cn1c(nnc1C12CCC(CC1)(CC2)c1nnc(o1)-c1ccc(F)cc1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C26H23F4N5O/c1-35-20(18-4-2-3-5-19(18)26(28,29)30)31-33-22(35)24-10-13-25(14-11-24,15-12-24)23-34-32-21(36-23)16-6-8-17(27)9-7-16/h2-9H,10-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibitory activity against mouse 11beta-HSD1				Bioorg Med Chem Lett 15: 5266-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.052 BindingDB Entry DOI: 10.7270/Q2QC031M
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50174292 (3-(4-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)bicy...) Show SMILES Cn1c(nnc1C12CCC(CC1)(CC2)c1nnc(o1)-c1ccc(F)cc1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C26H23F4N5O/c1-35-20(18-4-2-3-5-19(18)26(28,29)30)31-33-22(35)24-10-13-25(14-11-24,15-12-24)23-34-32-21(36-23)16-6-8-17(27)9-7-16/h2-9H,10-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibitory activity against human 11beta-HSD1				Bioorg Med Chem Lett 15: 5266-9 (2005) Article DOI: 10.1016/j.bmcl.2005.08.052 BindingDB Entry DOI: 10.7270/Q2QC031M
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50174292 (3-(4-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)bicy...) Show SMILES Cn1c(nnc1C12CCC(CC1)(CC2)c1nnc(o1)-c1ccc(F)cc1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C26H23F4N5O/c1-35-20(18-4-2-3-5-19(18)26(28,29)30)31-33-22(35)24-10-13-25(14-11-24,15-12-24)23-34-32-21(36-23)16-6-8-17(27)9-7-16/h2-9H,10-15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.24	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1				Bioorg Med Chem Lett 18: 2479-90 (2008) Article DOI: 10.1016/j.bmcl.2008.02.042 BindingDB Entry DOI: 10.7270/Q2QC04Q0
					More data for this Ligand-Target Pair