Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50195487'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195487 (4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N(C1CC1)C1CCCC1 Show InChI InChI=1S/C15H18Cl2N2O/c16-12-7-9(8-13(17)14(12)18)15(20)19(11-5-6-11)10-3-1-2-4-10/h7-8,10-11H,1-6,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPA				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Rattus norvegicus (rat))	BDBM50195487 (4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N(C1CC1)C1CCCC1 Show InChI InChI=1S/C15H18Cl2N2O/c16-12-7-9(8-13(17)14(12)18)15(20)19(11-5-6-11)10-3-1-2-4-10/h7-8,10-11H,1-6,18H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of rat 11beta-HSD1				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195487 (4-amino-3,5-dichloro-N-cyclopentyl-N-cyclopropylbe...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N(C1CC1)C1CCCC1 Show InChI InChI=1S/C15H18Cl2N2O/c16-12-7-9(8-13(17)14(12)18)15(20)19(11-5-6-11)10-3-1-2-4-10/h7-8,10-11H,1-6,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assay				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair