Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50195492'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195492 (3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methy...) Show SMILES C[C@@H]1C[C@@H](CCN1C(=O)c1cc(Cl)c(N)c(Cl)c1)n1c2ccccc2oc1=O Show InChI InChI=1S/C20H19Cl2N3O3/c1-11-8-13(25-16-4-2-3-5-17(16)28-20(25)27)6-7-24(11)19(26)12-9-14(21)18(23)15(22)10-12/h2-5,9-11,13H,6-8,23H2,1H3/t11-,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPA				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Rattus norvegicus (rat))	BDBM50195492 (3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methy...) Show SMILES C[C@@H]1C[C@@H](CCN1C(=O)c1cc(Cl)c(N)c(Cl)c1)n1c2ccccc2oc1=O Show InChI InChI=1S/C20H19Cl2N3O3/c1-11-8-13(25-16-4-2-3-5-17(16)28-20(25)27)6-7-24(11)19(26)12-9-14(21)18(23)15(22)10-12/h2-5,9-11,13H,6-8,23H2,1H3/t11-,13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of rat 11beta-HSD1				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195492 (3-((2R,4R)-1-(4-amino-3,5-dichlorobenzoyl)-2-methy...) Show SMILES C[C@@H]1C[C@@H](CCN1C(=O)c1cc(Cl)c(N)c(Cl)c1)n1c2ccccc2oc1=O Show InChI InChI=1S/C20H19Cl2N3O3/c1-11-8-13(25-16-4-2-3-5-17(16)28-20(25)27)6-7-24(11)19(26)12-9-14(21)18(23)15(22)10-12/h2-5,9-11,13H,6-8,23H2,1H3/t11-,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assay				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair