Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50195494'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195494 ((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N1CCCN(Cc2ccccc2)CCC1 Show InChI InChI=1S/C20H23Cl2N3O/c21-17-12-16(13-18(22)19(17)23)20(26)25-10-4-8-24(9-5-11-25)14-15-6-2-1-3-7-15/h1-3,6-7,12-13H,4-5,8-11,14,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in Escherichia coli by SPA				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Rattus norvegicus (rat))	BDBM50195494 ((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N1CCCN(Cc2ccccc2)CCC1 Show InChI InChI=1S/C20H23Cl2N3O/c21-17-12-16(13-18(22)19(17)23)20(26)25-10-4-8-24(9-5-11-25)14-15-6-2-1-3-7-15/h1-3,6-7,12-13H,4-5,8-11,14,23H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of rat 11beta-HSD1				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50195494 ((4-amino-3,5-dichlorophenyl)(5-benzyl-1,5-diazocan...) Show SMILES Nc1c(Cl)cc(cc1Cl)C(=O)N1CCCN(Cc2ccccc2)CCC1 Show InChI InChI=1S/C20H23Cl2N3O/c21-17-12-16(13-18(22)19(17)23)20(26)25-10-4-8-24(9-5-11-25)14-15-6-2-1-3-7-15/h1-3,6-7,12-13H,4-5,8-11,14,23H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells by fluorescence polarization immuno-assay				Bioorg Med Chem Lett 16: 6241-5 (2006) Article DOI: 10.1016/j.bmcl.2006.09.035 BindingDB Entry DOI: 10.7270/Q2B857R4
					More data for this Ligand-Target Pair