Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50239594'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50239594 (CHEMBL4059917) Show SMILES Cc1cccc(c1)C1(CC(=O)N2CC(O)C2)C2CC3CC1CC(C2)C3O |TLB:19:18:7.20.21:23,8:7:23:17.18.24,5:7:17.19.18:21.22.23,THB:25:24:7.20.21:23,19:20:23:17.18.24,24:18:7:21.22.23,24:22:7:17.19.18,8:7:17.19.18:21.22.23,5:7:23:17.18.24,(74.67,-38.9,;73.34,-38.12,;71.99,-38.88,;70.67,-38.1,;70.68,-36.56,;72.03,-35.81,;73.35,-36.59,;72.04,-34.27,;70.9,-33.24,;69.43,-33.71,;69.11,-35.22,;68.29,-32.68,;68.21,-31.14,;66.67,-31.22,;65.53,-30.19,;66.75,-32.76,;73.24,-33,;74.57,-33.49,;75.96,-33.14,;74.96,-34.42,;73.54,-33.85,;73.54,-32.27,;74.58,-31.03,;73.23,-31.51,;75.98,-31.61,;77.27,-30.77,)| Show InChI InChI=1S/C22H29NO3/c1-13-3-2-4-16(5-13)22(10-20(25)23-11-19(24)12-23)17-6-14-7-18(22)9-15(8-17)21(14)26/h2-5,14-15,17-19,21,24,26H,6-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human microsomes using [3H]cortisone as substrate preincubated for 10 mins followed by substrate addition measured after...				J Med Chem 60: 4932-4948 (2017) Article DOI: 10.1021/acs.jmedchem.7b00211 BindingDB Entry DOI: 10.7270/Q2DV1N23
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50239594 (CHEMBL4059917) Show SMILES Cc1cccc(c1)C1(CC(=O)N2CC(O)C2)C2CC3CC1CC(C2)C3O |TLB:19:18:7.20.21:23,8:7:23:17.18.24,5:7:17.19.18:21.22.23,THB:25:24:7.20.21:23,19:20:23:17.18.24,24:18:7:21.22.23,24:22:7:17.19.18,8:7:17.19.18:21.22.23,5:7:23:17.18.24,(74.67,-38.9,;73.34,-38.12,;71.99,-38.88,;70.67,-38.1,;70.68,-36.56,;72.03,-35.81,;73.35,-36.59,;72.04,-34.27,;70.9,-33.24,;69.43,-33.71,;69.11,-35.22,;68.29,-32.68,;68.21,-31.14,;66.67,-31.22,;65.53,-30.19,;66.75,-32.76,;73.24,-33,;74.57,-33.49,;75.96,-33.14,;74.96,-34.42,;73.54,-33.85,;73.54,-32.27,;74.58,-31.03,;73.23,-31.51,;75.98,-31.61,;77.27,-30.77,)| Show InChI InChI=1S/C22H29NO3/c1-13-3-2-4-16(5-13)22(10-20(25)23-11-19(24)12-23)17-6-14-7-18(22)9-15(8-17)21(14)26/h2-5,14-15,17-19,21,24,26H,6-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				J Med Chem 60: 4932-4948 (2017) Article DOI: 10.1021/acs.jmedchem.7b00211 BindingDB Entry DOI: 10.7270/Q2DV1N23
					More data for this Ligand-Target Pair