Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50260746'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50260746 (3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-(2-(tr...) Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17ClF3N3/c1-27-17(15-5-2-3-6-16(15)20(22,23)24)25-26-18(27)19(11-4-12-19)13-7-9-14(21)10-8-13/h2-3,5-10H,4,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human 11beta HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3405-11 (2008) Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50260746 (3-(1-(4-chlorophenyl)cyclobutyl)-4-methyl-5-(2-(tr...) Show SMILES Cn1c(nnc1C1(CCC1)c1ccc(Cl)cc1)-c1ccccc1C(F)(F)F Show InChI InChI=1S/C20H17ClF3N3/c1-27-17(15-5-2-3-6-16(15)20(22,23)24)25-26-18(27)19(11-4-12-19)13-7-9-14(21)10-8-13/h2-3,5-10H,4,11-12H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of mouse 11beta HSD1 by SPA assay				Bioorg Med Chem Lett 18: 3405-11 (2008) Article DOI: 10.1016/j.bmcl.2008.04.013 BindingDB Entry DOI: 10.7270/Q2XP74QM
					More data for this Ligand-Target Pair