Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50313299'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50313299 ((1S,5R)-8-(4-tert-butylphenylsulfonyl)-1-methyl-8-...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@@H]2CC[C@@]1(C)CC(O)(O)C2 |r| Show InChI InChI=1S/C18H27NO4S/c1-16(2,3)13-5-7-15(8-6-13)24(22,23)19-14-9-10-17(19,4)12-18(20,21)11-14/h5-8,14,20-21H,9-12H2,1-4H3/t14-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from mouse 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50313299 ((1S,5R)-8-(4-tert-butylphenylsulfonyl)-1-methyl-8-...) Show SMILES CC(C)(C)c1ccc(cc1)S(=O)(=O)N1[C@@H]2CC[C@@]1(C)CC(O)(O)C2 |r| Show InChI InChI=1S/C18H27NO4S/c1-16(2,3)13-5-7-15(8-6-13)24(22,23)19-14-9-10-17(19,4)12-18(20,21)11-14/h5-8,14,20-21H,9-12H2,1-4H3/t14-,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cortisone from human 11beta-HSD1 expressed in baculovirus-infected Sf9 cells after 1 hr by scintillation proximity assay				Bioorg Med Chem Lett 20: 1551-4 (2010) Article DOI: 10.1016/j.bmcl.2010.01.082 BindingDB Entry DOI: 10.7270/Q2NV9JC3
					More data for this Ligand-Target Pair