Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50329301'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50329301 ((R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carbo...) Show SMILES CC(C)(C)OC(=O)N[C@@H]1CCN(C1)C(=O)O[C@H]1C2CC3CC1C[C@](C3)(C2)C(C)(C)O |r,wU:8.7,16.16,wD:23.29,TLB:16:17:24:20.21.22,15:16:24.19.20:22,THB:18:19:22:25.17.16,18:17:24.19.20:22,16:21:24:25.18.17,(22.08,-44.56,;20.54,-44.53,;19.79,-43.19,;21.3,-43.19,;19.75,-45.85,;18.21,-45.83,;17.46,-44.48,;17.42,-47.15,;15.88,-47.12,;14.99,-45.86,;13.52,-46.32,;13.5,-47.86,;14.95,-48.36,;12.15,-48.62,;12.14,-50.16,;10.83,-47.84,;9.49,-48.6,;9.48,-50.12,;8.46,-51.4,;7.06,-50.84,;7.05,-49.25,;8.09,-48.02,;6.74,-48.49,;6.75,-49.98,;5.56,-51.26,;8.08,-50.47,;5.41,-49.2,;4.64,-47.86,;6.18,-47.86,;4.07,-49.98,)| Show InChI InChI=1S/C23H38N2O5/c1-21(2,3)30-19(26)24-17-6-7-25(13-17)20(27)29-18-15-8-14-9-16(18)12-23(10-14,11-15)22(4,5)28/h14-18,28H,6-13H2,1-5H3,(H,24,26)/t14?,15?,16?,17-,18-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of recombinant 11betaHSD1 expressed in CHO cells assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate reader				Bioorg Med Chem Lett 20: 6725-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.142 BindingDB Entry DOI: 10.7270/Q2X92BJ5
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50329301 ((R)-3-tert-Butoxycarbonylamino-pyrrolidine-1-carbo...) Show SMILES CC(C)(C)OC(=O)N[C@@H]1CCN(C1)C(=O)O[C@H]1C2CC3CC1C[C@](C3)(C2)C(C)(C)O |r,wU:8.7,16.16,wD:23.29,TLB:16:17:24:20.21.22,15:16:24.19.20:22,THB:18:19:22:25.17.16,18:17:24.19.20:22,16:21:24:25.18.17,(22.08,-44.56,;20.54,-44.53,;19.79,-43.19,;21.3,-43.19,;19.75,-45.85,;18.21,-45.83,;17.46,-44.48,;17.42,-47.15,;15.88,-47.12,;14.99,-45.86,;13.52,-46.32,;13.5,-47.86,;14.95,-48.36,;12.15,-48.62,;12.14,-50.16,;10.83,-47.84,;9.49,-48.6,;9.48,-50.12,;8.46,-51.4,;7.06,-50.84,;7.05,-49.25,;8.09,-48.02,;6.74,-48.49,;6.75,-49.98,;5.56,-51.26,;8.08,-50.47,;5.41,-49.2,;4.64,-47.86,;6.18,-47.86,;4.07,-49.98,)| Show InChI InChI=1S/C23H38N2O5/c1-21(2,3)30-19(26)24-17-6-7-25(13-17)20(27)29-18-15-8-14-9-16(18)12-23(10-14,11-15)22(4,5)28/h14-18,28H,6-13H2,1-5H3,(H,24,26)/t14?,15?,16?,17-,18-,23-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of 11betaHSD1 in human platelet assessed as [3H]-cortisone to [3H]-cortisol by microscintillation plate reader				Bioorg Med Chem Lett 20: 6725-9 (2010) Article DOI: 10.1016/j.bmcl.2010.08.142 BindingDB Entry DOI: 10.7270/Q2X92BJ5
					More data for this Ligand-Target Pair