Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50340436'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50340436 ((3,4-dihydroquinolin-1(2H)-yl)(4-(pyridin-3-yl)pip...) Show SMILES O=C(N1CCC(CC1)c1cccnc1)N1CCCc2ccccc12 Show InChI InChI=1S/C20H23N3O/c24-20(23-12-4-7-17-5-1-2-8-19(17)23)22-13-9-16(10-14-22)18-6-3-11-21-15-18/h1-3,5-6,8,11,15-16H,4,7,9-10,12-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D, Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assay				Bioorg Med Chem Lett 21: 2244-51 (2011) Article DOI: 10.1016/j.bmcl.2011.02.111 BindingDB Entry DOI: 10.7270/Q26H4HQS
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50340436 ((3,4-dihydroquinolin-1(2H)-yl)(4-(pyridin-3-yl)pip...) Show SMILES O=C(N1CCC(CC1)c1cccnc1)N1CCCc2ccccc12 Show InChI InChI=1S/C20H23N3O/c24-20(23-12-4-7-17-5-1-2-8-19(17)23)22-13-9-16(10-14-22)18-6-3-11-21-15-18/h1-3,5-6,8,11,15-16H,4,7,9-10,12-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D, Curated by ChEMBL					Assay Description Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assay				Bioorg Med Chem Lett 21: 2244-51 (2011) Article DOI: 10.1016/j.bmcl.2011.02.111 BindingDB Entry DOI: 10.7270/Q26H4HQS
					More data for this Ligand-Target Pair