Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50340441'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50340441 ((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(2H-benzo[b][1...) Show SMILES O=C(N1CCC(C1)c1cn[nH]c1)N1CCOc2ccccc12 Show InChI InChI=1S/C16H18N4O2/c21-16(19-6-5-12(11-19)13-9-17-18-10-13)20-7-8-22-15-4-2-1-3-14(15)20/h1-4,9-10,12H,5-8,11H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D, Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assay				Bioorg Med Chem Lett 21: 2244-51 (2011) Article DOI: 10.1016/j.bmcl.2011.02.111 BindingDB Entry DOI: 10.7270/Q26H4HQS
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50340441 ((3-(1H-pyrazol-4-yl)pyrrolidin-1-yl)(2H-benzo[b][1...) Show SMILES O=C(N1CCC(C1)c1cn[nH]c1)N1CCOc2ccccc12 Show InChI InChI=1S/C16H18N4O2/c21-16(19-6-5-12(11-19)13-9-17-18-10-13)20-7-8-22-15-4-2-1-3-14(15)20/h1-4,9-10,12H,5-8,11H2,(H,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D, Curated by ChEMBL					Assay Description Inhibition of mouse recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assay				Bioorg Med Chem Lett 21: 2244-51 (2011) Article DOI: 10.1016/j.bmcl.2011.02.111 BindingDB Entry DOI: 10.7270/Q26H4HQS
					More data for this Ligand-Target Pair