Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50340452'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50340452 ((4-(1,2,4-oxadiazol-3-yl)piperidin-1-yl)(3,4-dihyd...) Show SMILES O=C(N1CCC(CC1)c1ncon1)N1CCCc2ccccc12 Show InChI InChI=1S/C17H20N4O2/c22-17(21-9-3-5-13-4-1-2-6-15(13)21)20-10-7-14(8-11-20)16-18-12-23-19-16/h1-2,4,6,12,14H,3,5,7-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	378	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D, Curated by ChEMBL					Assay Description Inhibition of human recombinant 11beta-HSD1 assessed as conversion of radiolabelled-cortisone to cortisol by scintillation proximity assay				Bioorg Med Chem Lett 21: 2244-51 (2011) Article DOI: 10.1016/j.bmcl.2011.02.111 BindingDB Entry DOI: 10.7270/Q26H4HQS
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