Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50356446'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50356446 (CHEMBL1911700) Show SMILES Clc1ccccc1CSc1[nH]c(=O)c(C#N)c2CCOCc12 Show InChI InChI=1S/C16H13ClN2O2S/c17-14-4-2-1-3-10(14)9-22-16-13-8-21-6-5-11(13)12(7-18)15(20)19-16/h1-4H,5-6,8-9H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation plate reader				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50356446 (CHEMBL1911700) Show SMILES Clc1ccccc1CSc1[nH]c(=O)c(C#N)c2CCOCc12 Show InChI InChI=1S/C16H13ClN2O2S/c17-14-4-2-1-3-10(14)9-22-16-13-8-21-6-5-11(13)12(7-18)15(20)19-16/h1-4H,5-6,8-9H2,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1				Bioorg Med Chem Lett 21: 6693-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.058 BindingDB Entry DOI: 10.7270/Q2FN16M4
					More data for this Ligand-Target Pair