Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50382821'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50382821 (CHEMBL2023586) Show SMILES Clc1ccc2NC(=O)N(CC3CCN(CC3)C(=O)N(C3CC3)C3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C24H33ClN4O4S/c25-18-7-10-21-22(15-18)34(32,33)28(23(30)26-21)16-17-11-13-27(14-12-17)24(31)29(20-8-9-20)19-5-3-1-2-4-6-19/h7,10,15,17,19-20H,1-6,8-9,11-14,16H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	517	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50382821 (CHEMBL2023586) Show SMILES Clc1ccc2NC(=O)N(CC3CCN(CC3)C(=O)N(C3CC3)C3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C24H33ClN4O4S/c25-18-7-10-21-22(15-18)34(32,33)28(23(30)26-21)16-17-11-13-27(14-12-17)24(31)29(20-8-9-20)19-5-3-1-2-4-6-19/h7,10,15,17,19-20H,1-6,8-9,11-14,16H2,(H,26,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair