Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50382831'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50382831 (CHEMBL2023431) Show SMILES Clc1ccc2NC(=O)N(CC3CCN(CC3)C(=O)NC3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C21H29ClN4O4S/c22-16-7-8-18-19(13-16)31(29,30)26(21(28)24-18)14-15-9-11-25(12-10-15)20(27)23-17-5-3-1-2-4-6-17/h7-8,13,15,17H,1-6,9-12,14H2,(H,23,27)(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50382831 (CHEMBL2023431) Show SMILES Clc1ccc2NC(=O)N(CC3CCN(CC3)C(=O)NC3CCCCCC3)S(=O)(=O)c2c1 Show InChI InChI=1S/C21H29ClN4O4S/c22-16-7-8-18-19(13-16)31(29,30)26(21(28)24-18)14-15-9-11-25(12-10-15)20(27)23-17-5-3-1-2-4-6-17/h7-8,13,15,17H,1-6,9-12,14H2,(H,23,27)(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	283	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [3H]cortisol production after 60 mins by SPA				Bioorg Med Chem Lett 22: 2748-52 (2012) Article DOI: 10.1016/j.bmcl.2012.02.095 BindingDB Entry DOI: 10.7270/Q22F7PGX
					More data for this Ligand-Target Pair