Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50400151'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50400151 (CHEMBL2179454) Show SMILES OCCNc1ncc(C(=O)N[C@H]2C3CC4CC2C[C@](O)(C4)C3)c(n1)C1CCC1 |r,wU:11.10,wD:18.19,TLB:19:18:11:15.14.13,10:11:21.17.18:15.14.13,10:11:13:21.18.20,THB:19:18:11.16.15:13,20:18:11:15.14.13,20:14:11:21.17.18,17:16:13:21.18.20,17:18:11.16.15:13,(22.32,-30.16,;23.66,-30.94,;23.66,-32.48,;24.99,-33.24,;26.33,-32.48,;26.33,-30.93,;27.66,-30.16,;29,-30.93,;30.33,-30.15,;30.33,-28.61,;31.66,-30.92,;33,-30.14,;32.99,-28.39,;31.96,-27.31,;32.61,-26.04,;32.63,-27.48,;33.8,-28.81,;35.21,-28.25,;35.07,-26.62,;36.6,-26.63,;34.02,-25.5,;34.29,-27.84,;29,-32.48,;27.67,-33.25,;30.34,-33.24,;30.74,-34.73,;32.22,-34.33,;31.82,-32.84,)| Show InChI InChI=1S/C21H30N4O3/c26-5-4-22-20-23-11-16(18(25-20)13-2-1-3-13)19(27)24-17-14-6-12-7-15(17)10-21(28,8-12)9-14/h11-15,17,26,28H,1-10H2,(H,24,27)(H,22,23,25)/t12?,14?,15?,17-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50400151 (CHEMBL2179454) Show SMILES OCCNc1ncc(C(=O)N[C@H]2C3CC4CC2C[C@](O)(C4)C3)c(n1)C1CCC1 |r,wU:11.10,wD:18.19,TLB:19:18:11:15.14.13,10:11:21.17.18:15.14.13,10:11:13:21.18.20,THB:19:18:11.16.15:13,20:18:11:15.14.13,20:14:11:21.17.18,17:16:13:21.18.20,17:18:11.16.15:13,(22.32,-30.16,;23.66,-30.94,;23.66,-32.48,;24.99,-33.24,;26.33,-32.48,;26.33,-30.93,;27.66,-30.16,;29,-30.93,;30.33,-30.15,;30.33,-28.61,;31.66,-30.92,;33,-30.14,;32.99,-28.39,;31.96,-27.31,;32.61,-26.04,;32.63,-27.48,;33.8,-28.81,;35.21,-28.25,;35.07,-26.62,;36.6,-26.63,;34.02,-25.5,;34.29,-27.84,;29,-32.48,;27.67,-33.25,;30.34,-33.24,;30.74,-34.73,;32.22,-34.33,;31.82,-32.84,)| Show InChI InChI=1S/C21H30N4O3/c26-5-4-22-20-23-11-16(18(25-20)13-2-1-3-13)19(27)24-17-14-6-12-7-15(17)10-21(28,8-12)9-14/h11-15,17,26,28H,1-10H2,(H,24,27)(H,22,23,25)/t12?,14?,15?,17-,21-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair