Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50400172'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50400172 (CHEMBL2179021) Show SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cnc(N[C@@H]4CCC(=O)NC4)nc1C1CCCC1)C(C3)C2 |r,wU:7.8,wD:1.0,16.16,TLB:0:1:7:31.3.4,8:7:6.32.1:31.3.4,8:7:4:6.1.2,THB:0:1:7.30.31:4,2:1:7:31.3.4,2:3:7:6.32.1,32:30:4:6.1.2,32:1:7.30.31:4,(18.58,-4.69,;17.05,-4.67,;16.01,-3.55,;14.59,-4.1,;13.94,-5.37,;14.97,-6.45,;16.27,-5.89,;14.98,-8.19,;13.65,-8.97,;12.31,-8.2,;12.31,-6.66,;10.98,-8.98,;9.65,-8.21,;8.32,-8.98,;8.32,-10.53,;6.98,-11.3,;5.65,-10.53,;4.31,-11.29,;2.98,-10.51,;2.99,-8.97,;1.66,-8.19,;4.32,-8.21,;5.65,-8.98,;9.65,-11.3,;10.99,-10.53,;12.32,-11.29,;12.49,-12.82,;14,-13.14,;14.76,-11.8,;13.73,-10.66,;15.78,-6.86,;14.61,-5.54,;17.19,-6.3,)| Show InChI InChI=1S/C25H35N5O3/c31-20-6-5-18(12-26-20)28-24-27-13-19(22(30-24)15-3-1-2-4-15)23(32)29-21-16-7-14-8-17(21)11-25(33,9-14)10-16/h13-18,21,33H,1-12H2,(H,26,31)(H,29,32)(H,27,28,30)/t14?,16?,17?,18-,21-,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50400172 (CHEMBL2179021) Show SMILES O[C@@]12CC3CC(C1)[C@H](NC(=O)c1cnc(N[C@@H]4CCC(=O)NC4)nc1C1CCCC1)C(C3)C2 |r,wU:7.8,wD:1.0,16.16,TLB:0:1:7:31.3.4,8:7:6.32.1:31.3.4,8:7:4:6.1.2,THB:0:1:7.30.31:4,2:1:7:31.3.4,2:3:7:6.32.1,32:30:4:6.1.2,32:1:7.30.31:4,(18.58,-4.69,;17.05,-4.67,;16.01,-3.55,;14.59,-4.1,;13.94,-5.37,;14.97,-6.45,;16.27,-5.89,;14.98,-8.19,;13.65,-8.97,;12.31,-8.2,;12.31,-6.66,;10.98,-8.98,;9.65,-8.21,;8.32,-8.98,;8.32,-10.53,;6.98,-11.3,;5.65,-10.53,;4.31,-11.29,;2.98,-10.51,;2.99,-8.97,;1.66,-8.19,;4.32,-8.21,;5.65,-8.98,;9.65,-11.3,;10.99,-10.53,;12.32,-11.29,;12.49,-12.82,;14,-13.14,;14.76,-11.8,;13.73,-10.66,;15.78,-6.86,;14.61,-5.54,;17.19,-6.3,)| Show InChI InChI=1S/C25H35N5O3/c31-20-6-5-18(12-26-20)28-24-27-13-19(22(30-24)15-3-1-2-4-15)23(32)29-21-16-7-14-8-17(21)11-25(33,9-14)10-16/h13-18,21,33H,1-12H2,(H,26,31)(H,29,32)(H,27,28,30)/t14?,16?,17?,18-,21-,25-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	133	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 by HTRF assay				J Med Chem 55: 10652-61 (2012) Article DOI: 10.1021/jm3013163 BindingDB Entry DOI: 10.7270/Q2BG2Q4S
					More data for this Ligand-Target Pair