Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50426487'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50426487 (CHEMBL2322708) Show SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(s1)[C@](C)(O)C(F)(F)F)c1ccc(cc1C(F)(F)F)C(N)=O |r| Show InChI InChI=1S/C20H21F6N3O4S2/c1-11-10-28(14-4-3-12(17(27)30)9-13(14)19(21,22)23)7-8-29(11)35(32,33)16-6-5-15(34-16)18(2,31)20(24,25)26/h3-6,9,11,31H,7-8,10H2,1-2H3,(H2,27,30)/t11-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...				ACS Med Chem Lett 4: 118-23 (2013) Article DOI: 10.1021/ml300352x BindingDB Entry DOI: 10.7270/Q25B03TM
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50426487 (CHEMBL2322708) Show SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(s1)[C@](C)(O)C(F)(F)F)c1ccc(cc1C(F)(F)F)C(N)=O |r| Show InChI InChI=1S/C20H21F6N3O4S2/c1-11-10-28(14-4-3-12(17(27)30)9-13(14)19(21,22)23)7-8-29(11)35(32,33)16-6-5-15(34-16)18(2,31)20(24,25)26/h3-6,9,11,31H,7-8,10H2,1-2H3,(H2,27,30)/t11-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...				ACS Med Chem Lett 4: 118-23 (2013) Article DOI: 10.1021/ml300352x BindingDB Entry DOI: 10.7270/Q25B03TM
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50426487 (CHEMBL2322708) Show SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(s1)[C@](C)(O)C(F)(F)F)c1ccc(cc1C(F)(F)F)C(N)=O |r| Show InChI InChI=1S/C20H21F6N3O4S2/c1-11-10-28(14-4-3-12(17(27)30)9-13(14)19(21,22)23)7-8-29(11)35(32,33)16-6-5-15(34-16)18(2,31)20(24,25)26/h3-6,9,11,31H,7-8,10H2,1-2H3,(H2,27,30)/t11-,18+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse 11beta-HSD1 expressed in CHO cells using cortisol as substrate incubated for 30 mins prior to substrate addition measured after 1...				ACS Med Chem Lett 4: 118-23 (2013) Article DOI: 10.1021/ml300352x BindingDB Entry DOI: 10.7270/Q25B03TM
					More data for this Ligand-Target Pair