Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50432937'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50432937 (CHEMBL2377208) Show SMILES Cc1nc(NS(=O)(=O)c2ccc(cc2)-c2ccc(cc2)C#N)ccc1F Show InChI InChI=1S/C19H14FN3O2S/c1-13-18(20)10-11-19(22-13)23-26(24,25)17-8-6-16(7-9-17)15-4-2-14(12-21)3-5-15/h2-11H,1H3,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	194	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of 11beta-HSD1 in human HEK293 cells				Bioorg Med Chem Lett 23: 2344-8 (2013) Article DOI: 10.1016/j.bmcl.2013.02.066 BindingDB Entry DOI: 10.7270/Q29P3314
					More data for this Ligand-Target Pair