Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50440403'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50440403 (CHEMBL2425593) Show SMILES COc1ccc(cc1[N+]([O-])=O)S(=O)(=O)N1CCN(CC1)c1nc2ccccc2n1C Show InChI InChI=1S/C19H21N5O5S/c1-21-16-6-4-3-5-15(16)20-19(21)22-9-11-23(12-10-22)30(27,28)14-7-8-18(29-2)17(13-14)24(25)26/h3-8,13H,9-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leopold-Franzens-Universit£t Curated by ChEMBL					Assay Description Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as [1,2-3H]-cortisone reduction to [1,2,6,7-3H]-cortisol after 10 mins in presence...				Bioorg Med Chem Lett 23: 5397-400 (2013) Article DOI: 10.1016/j.bmcl.2013.07.047 BindingDB Entry DOI: 10.7270/Q2MK6F9R
					More data for this Ligand-Target Pair