Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50507375'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM50507375 (CHEMBL4457613) Show SMILES OC(C1CC1)c1cccn2c(nnc12)C1(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClN3O/c20-14-7-5-13(6-8-14)19(9-10-19)18-22-21-17-15(2-1-11-23(17)18)16(24)12-3-4-12/h1-2,5-8,11-12,16,24H,3-4,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant human 11beta-HSD1 expressed in HEK293 cell microsomes using [3H]cortisone as substrate after 4 hrs by homogeneous immuno-ra...				ACS Med Chem Lett 9: 1170-1174 (2018) Article DOI: 10.1021/acsmedchemlett.8b00307 BindingDB Entry DOI: 10.7270/Q20R9SP3
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Mus musculus (mouse))	BDBM50507375 (CHEMBL4457613) Show SMILES OC(C1CC1)c1cccn2c(nnc12)C1(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C19H18ClN3O/c20-14-7-5-13(6-8-14)19(9-10-19)18-22-21-17-15(2-1-11-23(17)18)16(24)12-3-4-12/h1-2,5-8,11-12,16,24H,3-4,9-10H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Curated by ChEMBL					Assay Description Inhibition of recombinant mouse 11beta-HSD1 expressed in HEK293 cell microsomes using [3H]cortisone as substrate after 4 hrs by homogeneous immuno-ra...				ACS Med Chem Lett 9: 1170-1174 (2018) Article DOI: 10.1021/acsmedchemlett.8b00307 BindingDB Entry DOI: 10.7270/Q20R9SP3
					More data for this Ligand-Target Pair