Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99342'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99342 (US8497281, 120 | US9120769, 53 | US9663470, 53) Show SMILES COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C24H26N2O2/c1-25-15-20(18-7-3-4-10-21(18)25)24(27)26-14-6-9-17-16-8-5-11-23(28-2)19(16)12-13-22(17)26/h3-5,7-8,10-11,15,17,22H,6,9,12-14H2,1-2H3/t17?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	979	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99342 (US8497281, 120 | US9120769, 53 | US9663470, 53) Show SMILES COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C24H26N2O2/c1-25-15-20(18-7-3-4-10-21(18)25)24(27)26-14-6-9-17-16-8-5-11-23(28-2)19(16)12-13-22(17)26/h3-5,7-8,10-11,15,17,22H,6,9,12-14H2,1-2H3/t17?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	979	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh US Patent					Assay Description In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...				US Patent US9663470 (2017) BindingDB Entry DOI: 10.7270/Q2V40X8H
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99342 (US8497281, 120 | US9120769, 53 | US9663470, 53) Show SMILES COc1cccc2C3CCCN([C@H]3CCc12)C(=O)c1cn(C)c2ccccc12 |r| Show InChI InChI=1S/C24H26N2O2/c1-25-15-20(18-7-3-4-10-21(18)25)24(27)26-14-6-9-17-16-8-5-11-23(28-2)19(16)12-13-22(17)26/h3-5,7-8,10-11,15,17,22H,6,9,12-14H2,1-2H3/t17?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	979	n/a	n/a	n/a	n/a	6.0	n/a
Boehringer-Ingelheim International GmbH US Patent					Assay Description n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...				US Patent US9120769 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HK9
					More data for this Ligand-Target Pair