Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99362'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99362 (US8497281, 140 | US9120769, 73 | US9663470, 73) Show SMILES Cn1cc(C(=O)N2CCCC3[C@@H]2CCc2ccccc32)c2ccccc12 |r| Show InChI InChI=1S/C23H24N2O/c1-24-15-20(19-9-4-5-11-21(19)24)23(26)25-14-6-10-18-17-8-3-2-7-16(17)12-13-22(18)25/h2-5,7-9,11,15,18,22H,6,10,12-14H2,1H3/t18?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	447	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99362 (US8497281, 140 | US9120769, 73 | US9663470, 73) Show SMILES Cn1cc(C(=O)N2CCCC3[C@@H]2CCc2ccccc32)c2ccccc12 |r| Show InChI InChI=1S/C23H24N2O/c1-24-15-20(19-9-4-5-11-21(19)24)23(26)25-14-6-10-18-17-8-3-2-7-16(17)12-13-22(18)25/h2-5,7-9,11,15,18,22H,6,10,12-14H2,1H3/t18?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	447	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh US Patent					Assay Description In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...				US Patent US9663470 (2017) BindingDB Entry DOI: 10.7270/Q2V40X8H
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99362 (US8497281, 140 | US9120769, 73 | US9663470, 73) Show SMILES Cn1cc(C(=O)N2CCCC3[C@@H]2CCc2ccccc32)c2ccccc12 |r| Show InChI InChI=1S/C23H24N2O/c1-24-15-20(19-9-4-5-11-21(19)24)23(26)25-14-6-10-18-17-8-3-2-7-16(17)12-13-22(18)25/h2-5,7-9,11,15,18,22H,6,10,12-14H2,1H3/t18?,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	447	n/a	n/a	n/a	n/a	6.0	n/a
Boehringer-Ingelheim International GmbH US Patent					Assay Description n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...				US Patent US9120769 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HK9
					More data for this Ligand-Target Pair