Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM99401'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99401 (US8497281, 179 | US9120769, 112 | US9663470, 112) Show SMILES Cc1cc2cc(ccc2[nH]1)C(=O)N1CCCC2[C@@H]1Cc1ccccc21 |r| Show InChI InChI=1S/C22H22N2O/c1-14-11-17-12-16(8-9-20(17)23-14)22(25)24-10-4-7-19-18-6-3-2-5-15(18)13-21(19)24/h2-3,5-6,8-9,11-12,19,21,23H,4,7,10,13H2,1H3/t19?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	724	n/a	n/a	n/a	n/a	6.0	37
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent					Assay Description In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...				US Patent US8497281 (2013) BindingDB Entry DOI: 10.7270/Q2G44NXT
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99401 (US8497281, 179 | US9120769, 112 | US9663470, 112) Show SMILES Cc1cc2cc(ccc2[nH]1)C(=O)N1CCCC2[C@@H]1Cc1ccccc21 |r| Show InChI InChI=1S/C22H22N2O/c1-14-11-17-12-16(8-9-20(17)23-14)22(25)24-10-4-7-19-18-6-3-2-5-15(18)13-21(19)24/h2-3,5-6,8-9,11-12,19,21,23H,4,7,10,13H2,1H3/t19?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	724	n/a	n/a	n/a	n/a	n/a	n/a
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International Gmbh US Patent					Assay Description In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...				US Patent US9663470 (2017) BindingDB Entry DOI: 10.7270/Q2V40X8H
					More data for this Ligand-Target Pair
11-beta-hydroxysteroid dehydrogenase 1 (Homo sapiens (Human))	BDBM99401 (US8497281, 179 | US9120769, 112 | US9663470, 112) Show SMILES Cc1cc2cc(ccc2[nH]1)C(=O)N1CCCC2[C@@H]1Cc1ccccc21 |r| Show InChI InChI=1S/C22H22N2O/c1-14-11-17-12-16(8-9-20(17)23-14)22(25)24-10-4-7-19-18-6-3-2-5-15(18)13-21(19)24/h2-3,5-6,8-9,11-12,19,21,23H,4,7,10,13H2,1H3/t19?,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	724	n/a	n/a	n/a	n/a	6.0	n/a
Boehringer-Ingelheim International GmbH US Patent					Assay Description n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...				US Patent US9120769 (2015) BindingDB Entry DOI: 10.7270/Q2XW4HK9
					More data for this Ligand-Target Pair